Microbial Organisms Pattern in Dialysis-Dependent Patients with Catheter-Related Bloodstream Infections at the Institute of Kidney Diseases, Peshawar
DOI:
https://doi.org/10.59736/IJP.24.02.1083Keywords:
Hemodialysis, catheter-related bloodstream infection, microbial pattern, Staphylococcus aureus, , vascular catheter, PeshawarAbstract
INTRODUCTIONCatheter-related bloodstream infections (CRBSIs) are among the most serious complications in patients undergoing hemodialysis through vascular catheters. These infections are associated with increased morbidity, prolonged hospitalization, higher healthcare costs, and mortality. Various microbial organisms are responsible for CRBSIs, and knowledge of the local microbial pattern is essential for early diagnosis, appropriate antibiotic selection, and better infection control practices.
OBJECTIVETo determine the frequency of microbial organisms pattern in patients with catheter-related bloodstream infections on hemodialysis.
MATERIALS AND METHODSThis cross-sectional study was conducted in the Nephrology Department of the Institute of Kidney Diseases (IKD), Hayatabad Medical Complex (HMC), Peshawar, from October 2025 to March 2026 over a period of six months after approval from CPSP and the institutional ethical review board. A total of 138 patients aged 25–70 years with CRBSIs on hemodialysis were included through consecutive non-probability sampling. Patients already receiving antibiotics, pregnant women, and patients with endocarditis were excluded. Demographic information, comorbidities, and catheter-related details were recorded on a structured proforma. Blood samples were obtained from catheter and peripheral sites for microbiological evaluation and identification of causative organisms. Data were analyzed using SPSS version 25.
RESULTS Gram-positive organisms were the most frequent causative agents of CRBSIs, particularly Staphylococcus aureus and Staphylococcus epidermidis. Gram-negative organisms including Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii, and Enterobacter cloacae were also isolated among hemodialysis patients with catheter-related infections. CONCLUSIONDetermination of the microbial organisms pattern in CRBSIs among hemodialysis patients will help clinicians select appropriate empirical antibiotics, improve infection control measures, and reduce catheter-associated morbidity and mortality in the local population.
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Copyright (c) 2026 Tassadaq Ali1, Sultan Zafar Akhtar2, Muhammad Faizan3, Ikram Ullah4, Faisal Hayat5 and Almas Khan6
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